Drug Name: | Mefenamic Acid |
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Drug Class: | Nonsteroidal Anti-inflammatory Drug (NSAID) |
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Mechanism of Action: | - Inhibits the production of prostaglandins by blocking the action of cyclooxygenase (COX) enzymes
- Prevents the formation of thromboxane A2, a potent vasoconstrictor and platelet aggregator
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Use: | - Relief of mild to moderate pain associated with menstrual cramps, headache, dental pain, musculoskeletal pain, and postoperative pain
- Reduction of fever
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Side Effects: | - Gastrointestinal disturbances such as nausea, vomiting, diarrhea, and abdominal pain
- Dizziness, headache, and drowsiness
- Allergic reactions such as rash, itching, and swelling
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Contraindications: | - Hypersensitivity to mefenamic acid or other NSAIDs
- History of asthma, urticaria, or other allergic-type reactions after taking aspirin or other NSAIDs
- Active peptic ulcer disease or gastrointestinal bleeding
- Severe renal impairment
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Specialty: | - Rheumatology
- Obstetrics and Gynecology
- Dentistry
- Emergency Medicine
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